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NSD1 in erythroid differentiation and leukemogenesis

We have uncovered a novel role for the nuclear receptor-binding SET domain protein 1 (NSD1) in human and murine erythroid differentiation. Mechanistically, we found that the histone methyltransferase activity of NSD1 is essential for chromatin binding, protein interactions and target gene activation...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Tauchmann, Samantha, Almosailleakh, Marwa, Schwaller, Juerg
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671059/
https://ncbi.nlm.nih.gov/pubmed/33235911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1809919
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