Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype

Chromosomal translocations involving the nucleoporin NUP98 have been described in several hematopoietic malignancies, in particular acute myeloid leukemia (AML). In the resulting chimeric proteins, Nup98's N-terminal region is fused to the C-terminal region of about 30 different partners, inclu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fahrenkrog, Birthe, Martinelli, Valérie, Nilles, Nadine, Fruhmann, Gernot, Chatel, Guillaume, Juge, Sabine, Sauder, Ursula, Di Giacomo, Danika, Mecucci, Cristina, Schwaller, Jürg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816316/
https://ncbi.nlm.nih.gov/pubmed/27031510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152321
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