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Blast crisis Ph+ chronic myeloid leukemia with NUP98/HOXA13 up-regulating MSI2
BACKGROUND: Musashi2(Msi2)-Numb pathway de-regulation is a molecular mechanism underlying the transition of chronic phase Ph + CML to deadly blast crisis, particularly in cases with a NUP98/HOXA9 fusion from a t(7;11)(p15;p15). This study provides new insights on the mechanisms cooperating in drivin...
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Main Authors: | , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
BioMed Central
2014
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4071805/ https://ncbi.nlm.nih.gov/pubmed/24971156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-7-42 |
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