A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

Constitutive activation of tyrosine kinases, such as the BCR/ABL fusion associated with t(9;22)(q34;q22), is a hallmark of chronic myeloid leukemia (CML) syndromes in humans. Expression of BCR/ABL is both necessary and sufficient to cause a chronic myeloproliferative syndrome in murine bone marrow t...

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Detalhes bibliográficos
Main Authors: Dash, Ajeeta B., Williams, Ifor R., Kutok, Jeffery L., Tomasson, Michael H., Anastasiadou, Ema, Lindahl, Kathleen, Li, Shaoguang, Van Etten, Richard A., Borrow, Julian, Housman, David, Druker, Brian, Gilliland, D. Gary
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124303/
https://ncbi.nlm.nih.gov/pubmed/12032333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102583199
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