A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

Constitutive activation of tyrosine kinases, such as the BCR/ABL fusion associated with t(9;22)(q34;q22), is a hallmark of chronic myeloid leukemia (CML) syndromes in humans. Expression of BCR/ABL is both necessary and sufficient to cause a chronic myeloproliferative syndrome in murine bone marrow t...

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Bibliografski detalji
Glavni autori: Dash, Ajeeta B., Williams, Ifor R., Kutok, Jeffery L., Tomasson, Michael H., Anastasiadou, Ema, Lindahl, Kathleen, Li, Shaoguang, Van Etten, Richard A., Borrow, Julian, Housman, David, Druker, Brian, Gilliland, D. Gary
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC124303/
https://ncbi.nlm.nih.gov/pubmed/12032333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102583199
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