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A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9
Constitutive activation of tyrosine kinases, such as the BCR/ABL fusion associated with t(9;22)(q34;q22), is a hallmark of chronic myeloid leukemia (CML) syndromes in humans. Expression of BCR/ABL is both necessary and sufficient to cause a chronic myeloproliferative syndrome in murine bone marrow t...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The National Academy of Sciences
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124303/ https://ncbi.nlm.nih.gov/pubmed/12032333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102583199 |
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