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IL-17 Induced Autophagy Regulates Mitochondrial Dysfunction and Fibrosis in Severe Asthmatic Bronchial Fibroblasts

The accumulation of fibroblasts, their synthesis of extracellular matrix (ECM) proteins and their innate resistance to apoptosis are characteristics of subepithelial fibrosis observed in severe asthma. Interleukin-17 (IL-17) is an important regulator of airway remodeling in asthma. However, the cont...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Al Heialy, Saba, Mahboub, Bassam, Ansari, Abdul Wahid, Hachim, Ibrahim Y., Rawat, Surendra, Salameh, Laila, Hachim, Mahmood Y., Olivenstein, Ronald, Halwani, Rabih, Hamoudi, Rifat, Hamid, Qutayba
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326148/
https://ncbi.nlm.nih.gov/pubmed/32670268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01002
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