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Presenilin 1 increases association with synaptotagmin 1 during normal aging
Presenilin 1 (PS1), the catalytic component of gamma secretase, associates with synaptotagmin 1 (Syt-1). This interaction is decreased in the brains of patients with sporadic Alzheimer’s disease. However, it remains unclear how this interaction changes during normal aging. Because aging is a risk fa...
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| Publicado en: | Neurobiol Aging |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7325863/ https://ncbi.nlm.nih.gov/pubmed/31864759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.10.006 |
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