T cell-expressed microRNA-155 reduces lifespan in a mouse model of age-related chronic inflammation

Aging-related chronic inflammation is a risk factor for many human disorders through incompletely understood mechanisms. Aged mice deficient in microRNA-146a succumb to life-shortening chronic inflammation. In this study, we report that miR-155 in T cells contributes to shortened lifespan of miR-146...

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Vydáno v:J Immunol
Hlavní autoři: Ekiz, H. Atakan, Ramstead, Andrew G., Lee, Soh-Hyun, Nelson, Morgan C., Bauer, Kaylyn M., Wallace, Jared A., Hu, Ruozhen, Round, June L., Rutter, Jared, Drummond, Micah J., Rao, Dinesh S., O’Connell, Ryan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325601/
https://ncbi.nlm.nih.gov/pubmed/32161096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901484
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