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A C3-specific nanobody that blocks all three activation pathways in the human and murine complement system

The complement system is a tightly controlled proteolytic cascade in the innate immune system, which tags intruding pathogens and dying host cells for clearance. An essential protein in this process is complement component C3. Uncontrolled complement activation has been implicated in several human d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Pedersen, Henrik, Jensen, Rasmus K., Hansen, Annette G., Gadeberg, Trine A. F., Thiel, Steffen, Laursen, Nick S., Andersen, Gregers R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324514/
https://ncbi.nlm.nih.gov/pubmed/32376685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012339
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