Llwytho...
A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement
The complement system is a complex, carefully regulated proteolytic cascade for which suppression of aberrant activation is of increasing clinical relevance, and inhibition of the complement alternative pathway is a subject of intense research. Here, we describe the nanobody hC3Nb1 that binds to mul...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Biol Chem |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Biochemistry and Molecular Biology
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5925797/ https://ncbi.nlm.nih.gov/pubmed/29497000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001179 |
| Tagiau: |
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