A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement

The complement system is a complex, carefully regulated proteolytic cascade for which suppression of aberrant activation is of increasing clinical relevance, and inhibition of the complement alternative pathway is a subject of intense research. Here, we describe the nanobody hC3Nb1 that binds to mul...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jensen, Rasmus K., Pihl, Rasmus, Gadeberg, Trine A. F., Jensen, Jan K., Andersen, Kasper R., Thiel, Steffen, Laursen, Nick S., Andersen, Gregers R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925797/
https://ncbi.nlm.nih.gov/pubmed/29497000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001179
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados