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Monitoring co-transcriptional folding of riboswitches through helicase unwinding

In the cell, RNAs fold and begin to function as they are being transcribed. In contrast, in the laboratory, RNAs are typically studied after transcription is completed. Co-transcriptional folding can regulate the function of riboswitches and ribozymes and dictate the order of ribonucleoprotein assem...

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Detalles Bibliográficos
Publicado en:Methods Enzymol
Main Authors: Jones, Christopher P., Panja, Subrata, Woodson, Sarah A., Ferré-D’Amaré, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324067/
https://ncbi.nlm.nih.gov/pubmed/31239047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.05.031
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