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Monitoring co-transcriptional folding of riboswitches through helicase unwinding

In the cell, RNAs fold and begin to function as they are being transcribed. In contrast, in the laboratory, RNAs are typically studied after transcription is completed. Co-transcriptional folding can regulate the function of riboswitches and ribozymes and dictate the order of ribonucleoprotein assem...

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Publicat a:Methods Enzymol
Autors principals: Jones, Christopher P., Panja, Subrata, Woodson, Sarah A., Ferré-D’Amaré, Adrian R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324067/
https://ncbi.nlm.nih.gov/pubmed/31239047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.05.031
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