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Monitoring co-transcriptional folding of riboswitches through helicase unwinding

In the cell, RNAs fold and begin to function as they are being transcribed. In contrast, in the laboratory, RNAs are typically studied after transcription is completed. Co-transcriptional folding can regulate the function of riboswitches and ribozymes and dictate the order of ribonucleoprotein assem...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Jones, Christopher P., Panja, Subrata, Woodson, Sarah A., Ferré-D’Amaré, Adrian R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324067/
https://ncbi.nlm.nih.gov/pubmed/31239047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.05.031
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