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Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase

The unwinding of nucleic acid secondary structures within cells is crucial to maintain genomic integrity and prevent abortive transcription and translation initiation. DHX36, also known as RHAU or G4R1, is a DEAH-box ATP-dependent helicase highly specific for DNA and RNA G-quadruplexes (G4s). A fund...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Chen, Michael C., Murat, Pierre, Abecassis, Keren, Ferré-D'Amaré, Adrian R., Balasubramanian, Shankar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344499/
https://ncbi.nlm.nih.gov/pubmed/25653156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv051
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