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Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
The unwinding of nucleic acid secondary structures within cells is crucial to maintain genomic integrity and prevent abortive transcription and translation initiation. DHX36, also known as RHAU or G4R1, is a DEAH-box ATP-dependent helicase highly specific for DNA and RNA G-quadruplexes (G4s). A fund...
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| Опубликовано в: : | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344499/ https://ncbi.nlm.nih.gov/pubmed/25653156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv051 |
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