Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin

Polymerized hemoglobin (PolyHb) is a promising hemoglobin (Hb)-based oxygen carrier currently undergoing development as a red blood cell substitute. Unfortunately, commercially developed products are composed of low-molecular-weight (LMW) PolyHb molecules, which extravasate, scavenge nitric oxide, a...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Belcher, Donald A., Munoz, Carlos, Pires, Ivan S., Williams, Alexander T., Cabrales, Pedro, Palmer, Andre F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Transfusion Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322967/
https://ncbi.nlm.nih.gov/pubmed/32559292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002045
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