Obstruction of Small Arterioles in Patients with Critical Limb Ischemia due to Partial Endothelial-to-Mesenchymal Transition

Critical limb ischemia (CLI) is a hazardous manifestation of atherosclerosis and treatment failure is common. Abnormalities in the arterioles might underlie this failure but the cellular pathobiology of microvessels in CLI is poorly understood. We analyzed 349 intramuscular arterioles in lower limb...

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Publicado en:iScience
Autores principales: Chevalier, Jacqueline, Yin, Hao, Arpino, John-Michael, O'Neil, Caroline, Nong, Zengxuan, Gilmore, Kevin J., Lee, Jason J., Prescott, Emma, Hewak, Matthew, Rice, Charles L., Dubois, Luc, Power, Adam H., Hamilton, Douglas W., Pickering, J. Geoffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322363/
https://ncbi.nlm.nih.gov/pubmed/32629616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101251
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