Obstruction of Small Arterioles in Patients with Critical Limb Ischemia due to Partial Endothelial-to-Mesenchymal Transition

Critical limb ischemia (CLI) is a hazardous manifestation of atherosclerosis and treatment failure is common. Abnormalities in the arterioles might underlie this failure but the cellular pathobiology of microvessels in CLI is poorly understood. We analyzed 349 intramuscular arterioles in lower limb...

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Publicado no:iScience
Main Authors: Chevalier, Jacqueline, Yin, Hao, Arpino, John-Michael, O'Neil, Caroline, Nong, Zengxuan, Gilmore, Kevin J., Lee, Jason J., Prescott, Emma, Hewak, Matthew, Rice, Charles L., Dubois, Luc, Power, Adam H., Hamilton, Douglas W., Pickering, J. Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322363/
https://ncbi.nlm.nih.gov/pubmed/32629616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101251
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