Seno-destructive smooth muscle cells in the ascending aorta of patients with bicuspid aortic valve disease

BACKGROUND: Ascending aortic aneurysms constitute an important hazard for individuals with a bicuspid aortic valve (BAV). However, the processes that degrade the aortic wall in BAV disease remain poorly understood. METHODS: We undertook in situ analysis of ascending aortas from 68 patients, seeking...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Balint, Brittany, Yin, Hao, Nong, Zengxuan, Arpino, John-Michael, O'Neil, Caroline, Rogers, Stephanie R., Randhawa, Varinder K., Fox, Stephanie A., Chevalier, Jacqueline, Lee, Jason J., Chu, Michael W.A., Pickering, J. Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562112/
https://ncbi.nlm.nih.gov/pubmed/31078518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.060
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