Obstruction of Small Arterioles in Patients with Critical Limb Ischemia due to Partial Endothelial-to-Mesenchymal Transition

Critical limb ischemia (CLI) is a hazardous manifestation of atherosclerosis and treatment failure is common. Abnormalities in the arterioles might underlie this failure but the cellular pathobiology of microvessels in CLI is poorly understood. We analyzed 349 intramuscular arterioles in lower limb...

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Publicat a:iScience
Autors principals: Chevalier, Jacqueline, Yin, Hao, Arpino, John-Michael, O'Neil, Caroline, Nong, Zengxuan, Gilmore, Kevin J., Lee, Jason J., Prescott, Emma, Hewak, Matthew, Rice, Charles L., Dubois, Luc, Power, Adam H., Hamilton, Douglas W., Pickering, J. Geoffrey
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322363/
https://ncbi.nlm.nih.gov/pubmed/32629616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101251
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