A Genome-Wide Association Study implicates the APOE locus in non-pathological cognitive ageing

Cognitive decline is a feared aspect of growing old. It is a major contributor to lower quality of life and loss of independence in old age. We investigated the genetic contribution to individual differences in non-pathological cognitive ageing in five cohorts of older adults. We undertook a genome-...

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Publicado en:Mol Psychiatry
Autores principales: Davies, Gail, Harris, Sarah E, Reynolds, Chandra A, Payton, Antony, Knight, Helen M, Liewald, David C, Lopez, Lorna M, Luciano, Michelle, Gow, Alan J, Corley, Janie, Henderson, Ross, Murray, Catherine, Pattie, Alison, Fox, Helen C., Redmond, Paul, Lutz, Michael W, Chiba-Falek, Ornit, Linnertz, Colton, Saith, Sunita, Haggarty, Paul, McNeill, Geraldine, Ke, Xiayi, Ollier, William, Horan, Michael, Roses, Allen D, Ponting, Chris P, Porteous, David J, Tenesa, Albert, Pickles, Andrew, Starr, John M, Whalley, Lawrence J, Pedersen, Nancy L, Pendleton, Neil, Visscher, Peter M, Deary, Ian J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321835/
https://ncbi.nlm.nih.gov/pubmed/23207651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.159
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