A Genome-Wide Association Study implicates the APOE locus in non-pathological cognitive ageing

Cognitive decline is a feared aspect of growing old. It is a major contributor to lower quality of life and loss of independence in old age. We investigated the genetic contribution to individual differences in non-pathological cognitive ageing in five cohorts of older adults. We undertook a genome-...

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Publié dans:Mol Psychiatry
Auteurs principaux: Davies, Gail, Harris, Sarah E, Reynolds, Chandra A, Payton, Antony, Knight, Helen M, Liewald, David C, Lopez, Lorna M, Luciano, Michelle, Gow, Alan J, Corley, Janie, Henderson, Ross, Murray, Catherine, Pattie, Alison, Fox, Helen C., Redmond, Paul, Lutz, Michael W, Chiba-Falek, Ornit, Linnertz, Colton, Saith, Sunita, Haggarty, Paul, McNeill, Geraldine, Ke, Xiayi, Ollier, William, Horan, Michael, Roses, Allen D, Ponting, Chris P, Porteous, David J, Tenesa, Albert, Pickles, Andrew, Starr, John M, Whalley, Lawrence J, Pedersen, Nancy L, Pendleton, Neil, Visscher, Peter M, Deary, Ian J
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7321835/
https://ncbi.nlm.nih.gov/pubmed/23207651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.159
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