miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Genomic instability (GI) predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high degree of genomic instability remain unclear. Here we report that miR-181a is able to transform fallopian tube secretory epithelial cells throu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Knarr, Matthew, Avelar, Rita A., Sekhar, Sreeja C., Kwiatkowski, Lily J., Dziubinski, Michele L., McAnulty, Jessica, Skala, Stephanie, Avril, Stefanie, Drapkin, Ronny, DiFeo, Analisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320168/
https://ncbi.nlm.nih.gov/pubmed/32591511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17030-w
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