miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Genomic instability (GI) predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high degree of genomic instability remain unclear. Here we report that miR-181a is able to transform fallopian tube secretory epithelial cells throu...

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Pubblicato in:Nat Commun
Autori principali: Knarr, Matthew, Avelar, Rita A., Sekhar, Sreeja C., Kwiatkowski, Lily J., Dziubinski, Michele L., McAnulty, Jessica, Skala, Stephanie, Avril, Stefanie, Drapkin, Ronny, DiFeo, Analisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320168/
https://ncbi.nlm.nih.gov/pubmed/32591511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17030-w
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