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Inhibition of Skp2 Sensitizes Chronic Myeloid Leukemia Cells to Imatinib
INTRODUCTION: Skp2 is an E3 ubiquitin ligase that plays an important role in modulating tumor progression. The mechanisms underlying Skp2 in the promotion of proliferation and its function in the primary resistance to tyrosine kinase inhibitors (TKIs) in human CML remain to be determined. This study...
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| Publicado no: | Cancer Manag Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319929/ https://ncbi.nlm.nih.gov/pubmed/32606967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S253367 |
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