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A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics
The transcription factors NF-κB and p53 are key regulators in the genotoxic stress response and are critical for tumor development. Although there is ample evidence for interactions between both networks, a comprehensive understanding of the crosstalk is lacking. Here, we developed a systematic appr...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319280/ https://ncbi.nlm.nih.gov/pubmed/32589666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007901 |
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