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Therapeutic and prophylactic deletion of IL‐4Ra‐signaling ameliorates established ovalbumin induced allergic asthma
BACKGROUND: Allergic asthma is a chronic inflammatory airway disease driven predominantly by a T(H)2 immune response to environmental allergens. IL‐4Rα‐signaling is essential for driving T(H)2‐type immunity to allergens. Anti‐T(H)2 therapies have the potential to effectively reduce airway obstructio...
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| Publicado no: | Allergy |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7318634/ https://ncbi.nlm.nih.gov/pubmed/31782803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14137 |
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