Interleukin-17 is a negative regulator of established allergic asthma

T helper (Th)17 cells producing interleukin (IL)-17 play a role in autoimmune and allergic inflammation. Here, we show that IL-23 induces IL-17 in the lung and IL-17 is required during antigen sensitization to develop allergic asthma, as shown in IL-17R–deficient mice. Since IL-17 expression increas...

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Detalhes bibliográficos
Main Authors: Schnyder-Candrian, Silvia, Togbe, Dieudonnée, Couillin, Isabelle, Mercier, Isabelle, Brombacher, Frank, Quesniaux, Valérie, Fossiez, Francois, Ryffel, Bernhard, Schnyder, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118159/
https://ncbi.nlm.nih.gov/pubmed/17101734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061401
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