Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription

8‐Oxoguanine DNA glycosylase1 (OGG1)‐initiated base excision repair (BER) is the primary pathway to remove the pre‐mutagenic 8‐oxo‐7,8‐dihydroguanine (8‐oxoG) from DNA. Recent studies documented 8‐oxoG serves as an epigenetic‐like mark and OGG1 modulates gene expression in oxidatively stressed cells...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Hao, Wenjing, Wang, Jing, Zhang, Yuanhang, Wang, Chenxin, Xia, Lan, Zhang, Wenhe, Zafar, Muhammad, Kang, Ju‐Yong, Wang, Ruoxi, Ali Bohio, Ameer, Pan, Lang, Zeng, Xianlu, Wei, Min, Boldogh, Istvan, Ba, Xueqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318607/
https://ncbi.nlm.nih.gov/pubmed/32378256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201902243R
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