c-Abl–Mediated Tyrosine Phosphorylation of PARP1 Is Crucial for Expression of Proinflammatory Genes

Poly(ADP-ribosyl)ation is a rapid and transient posttranslational protein modification mostly catalyzed by poly(ADP-ribose) polymerase-1 (PARP1). Fundamental roles of activated PARP1 in DNA damage repair and cellular response pathways are well established; however, the precise mechanisms by which PA...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bohio, Ameer Ali, Sattout, Aman, Wang, Ruoxi, Wang, Ke, Sah, Rajiv Kumar, Guo, Xiaolan, Zeng, Xianlu, Ke, Yueshuang, Boldogh, Istvan, Ba, Xueqing
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2019
Assuntos:
Innate Immunity and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731455/
https://ncbi.nlm.nih.gov/pubmed/31399520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801616
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