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Stereospecific Asymmetric Synthesis of Tertiary Allylic Alcohol Derivatives by Catalytic [2,3]‐Meisenheimer Rearrangements

Chiral acyclic tertiary allylic alcohols are very important synthetic building blocks, but their enantioselective synthesis is often challenging. A major limitation in catalytic asymmetric 1,2‐addition approaches to ketones is the enantioface differentiation by steric distinction of both ketone resi...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Yu, Xin, Wannenmacher, Nick, Peters, René
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318343/
https://ncbi.nlm.nih.gov/pubmed/32176404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001725
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