A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity

The limited efficacy of seasonal influenza vaccines is usually attributed to ongoing variation in the major antigenic targets for protective antibody responses including hemagglutinin (HA) and neuraminidase (NA). Hence, vaccine development has largely focused on broadening antigenic epitopes to gene...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Immunol
Κύριοι συγγραφείς: Sato-Kaneko, Fumi, Yao, Shiyin, Lao, Fitzgerald S., Shpigelman, Jonathan, Messer, Karen, Pu, Minya, Shukla, Nikunj M., Cottam, Howard B., Chan, Michael, Chu, Paul J., Burkhart, David, Schoener, Roman, Matsutani, Takaji, Carson, Dennis A., Corr, Maripat, Hayashi, Tomoko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2020
Θέματα:
Immunology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318308/
https://ncbi.nlm.nih.gov/pubmed/32636840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01207
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