Transaldolase haploinsufficiency in subjects with acetaminophen‐induced liver failure

Transaldolase (TAL) is an enzyme in the pentose phosphate pathway (PPP) that generates NADPH for protection against oxidative stress. While deficiency of other PPP enzymes, such as transketolase (TKT), are incompatible with mammalian cell survival, mice lacking TAL are viable and develop progressive...

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Detalhes bibliográficos
Publicado no:J Inherit Metab Dis
Main Authors: Oaks, Zachary, Jimah, John, Grossman, Craig C., Beckford, Miguel, Kelly, Ryan, Banerjee, Sanjay, Niland, Brian, Miklossy, Gabriella, Kuloglu, Zarife, Kansu, Aydan, Lee, William, Szonyi, Laszlo, Banki, Katalin, Perl, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317976/
https://ncbi.nlm.nih.gov/pubmed/31769880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12197
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