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Study of transaldolase deficiency in urine samples by capillary LC-MS/MS

Transaldolase (TAL) is a key enzyme of the pentose phosphate pathway (PPP). TAL deficiency is a newly recognized cause of liver cirrhosis. We have developed an ion-pair LC separation combined with negative ion electrospray MS/MS detection method to assess PPP metabolites in urine samples from TAL-de...

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Detalhes bibliográficos
Main Authors: Vas, György, Conkrite, Karina, Amidon, Wendy, Qian, Yueming, Bánki, Katalin, Perl, András
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127395/
https://ncbi.nlm.nih.gov/pubmed/16470722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.1004
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