Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine

Although oxidative stress has been implicated in acute acetaminophen-induced liver failure and in chronic liver cirrhosis and hepatocellular carcinoma (HCC), no common underlying metabolic pathway has been identified. Recent case reports suggest a link between the pentose phosphate pathway (PPP) enz...

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Главные авторы: Hanczko, Robert, Fernandez, David R., Doherty, Edward, Qian, Yueming, Vas, Gyorgy, Niland, Brian, Telarico, Tiffany, Garba, Adinoyi, Banerjee, Sanjay, Middleton, Frank A., Barrett, Donna, Barcza, Maureen, Banki, Katalin, Landas, Steve K., Perl, Andras
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689120/
https://ncbi.nlm.nih.gov/pubmed/19436114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35722
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