Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice

Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon...

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Publicado en:Front Physiol
Main Authors: Moore, Timothy M., Lin, Amanda J., Strumwasser, Alexander R., Cory, Kevin, Whitney, Kate, Ho, Theodore, Ho, Timothy, Lee, Joseph L., Rucker, Daniel H., Nguyen, Christina Q., Yackly, Aidan, Mahata, Sushil K., Wanagat, Jonathan, Stiles, Linsey, Turcotte, Lorraine P., Crosbie, Rachelle H., Zhou, Zhenqi
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317021/
https://ncbi.nlm.nih.gov/pubmed/32636760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00690
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