Characterization of brain dystrophins absence and impact in dystrophin-deficient Dmd(mdx) rat model

Duchenne Muscular Dystrophy (DMD) is a severe muscle-wasting disease caused by mutations in the DMD gene encoding dystrophin, expressed mainly in muscles but also in other tissues like retina and brain. Non-progressing cognitive dysfunction occurs in 20 to 50% of DMD patients. Furthermore, loss of e...

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Publicat a:PLoS One
Autors principals: Caudal, Dorian, François, Virginie, Lafoux, Aude, Ledevin, Mireille, Anegon, Ignacio, Le Guiner, Caroline, Larcher, Thibaut, Huchet, Corinne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065776/
https://ncbi.nlm.nih.gov/pubmed/32160266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230083
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