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Preferred drifting along the DNA major groove and cooperative anchoring of the p53 core domain: mechanisms and scenarios

While the importance of specific p53-DNA binding is broadly accepted, the recognition process is still not fully understood. Figuring out the initial tetrameric p53-DNA association and the swift and cooperative search for specific binding sites is crucial for understanding the transactivation mechan...

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Detalhes bibliográficos
Publicado no:J Mol Recognit
Main Authors: Pan, Yongping, Nussinov, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316384/
https://ncbi.nlm.nih.gov/pubmed/19856322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.990
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