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EPCR deficiency or function-blocking antibody protects against joint bleeding–induced pathology in hemophilia mice

We recently showed that clotting factor VIIa (FVIIa) binding to endothelial cell protein C receptor (EPCR) induces anti-inflammatory signaling and protects vascular barrier integrity. Inflammation and vascular permeability are thought to be major contributors to the development of hemophilic arthrop...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Magisetty, Jhansi, Pendurthi, Usha R., Esmon, Charles T., Rao, L. Vijaya Mohan
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316205/
https://ncbi.nlm.nih.gov/pubmed/32294155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003824
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