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Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophilia therapy: mode of its action
Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of recombinant FVIIa (rFVIIa) in therapeutic conditions. The present study is carried out to inve...
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| Publicado no: | Blood Adv |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5602564/ https://ncbi.nlm.nih.gov/pubmed/28932824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016004143 |
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