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Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect
Recombinant factor FVIIa (rFVIIa) is used as a hemostatic agent to treat bleeding disorders in hemophilia patients with inhibitors and other groups of patients. Our recent studies showed that FVIIa binds endothelial cell protein C receptor (EPCR) and induces protease-activated receptor 1 (PAR1)-medi...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8212509/ https://ncbi.nlm.nih.gov/pubmed/33534910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008417 |
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