Factor VIIa induces extracellular vesicles from the endothelium: a potential mechanism for its hemostatic effect

Recombinant factor FVIIa (rFVIIa) is used as a hemostatic agent to treat bleeding disorders in hemophilia patients with inhibitors and other groups of patients. Our recent studies showed that FVIIa binds endothelial cell protein C receptor (EPCR) and induces protease-activated receptor 1 (PAR1)-medi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Das, Kaushik, Keshava, Shiva, Ansari, Shabbir A., Kondreddy, Vijay, Esmon, Charles T., Griffin, John H., Pendurthi, Usha R., Rao, L. Vijaya Mohan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2021
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212509/
https://ncbi.nlm.nih.gov/pubmed/33534910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008417
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky