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Proton-Electron Transfer to the Active Site Is Essential for the Reaction Mechanism of Soluble Δ(9)-Desaturase

Full understanding of the catalytic action of non-heme iron (NHFe) and non-heme diiron (NHFe(2)) enzymes is still beyond the grasp of contemporary computational and experimental techniques. Many of these enzymes exhibit fascinating chemo-, regio- and stereoselectivity, in spite of employing highly r...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Bím, Daniel, Chalupský, Jakub, Culka, Martin, Solomon, Edward I., Rulíšek, Lubomír, Srnec, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316153/
https://ncbi.nlm.nih.gov/pubmed/32406236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c01786
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