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Ribonucleotide Reductases (RNRs): Structure, chemistry, and metabolism suggest new therapeutic targets
Ribonucleotide reductases (RNRs) catalyze the de novo conversion of nucleotides to deoxynucleotides in all organisms, controlling their relative ratios and abundance and in doing so play an important role in fidelity of DNA replication and repair. RNR’s central role in nucleic acid metabolism has re...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Annu Rev Biochem |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7316142/ https://ncbi.nlm.nih.gov/pubmed/32569524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-013118-111843 |
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