Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression

The application of tumor immunotherapy to glioblastoma (GBM) is limited by an unprecedented degree of immune suppression due to factors that include high numbers of immune suppressive myeloid cells, the blood brain barrier, and T cell sequestration to the bone marrow. We previously identified an inc...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Alban, Tyler J., Bayik, Defne, Otvos, Balint, Rabljenovic, Anja, Leng, Lin, Jia-Shiun, Leu, Roversi, Gustavo, Lauko, Adam, Momin, Arbaz A., Mohammadi, Alireza M., Peereboom, David M., Ahluwalia, Manmeet S., Matsuda, Kazuko, Yun, Kyuson, Bucala, Richard, Vogelbaum, Michael A., Lathia, Justin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7315581/
https://ncbi.nlm.nih.gov/pubmed/32625208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01191
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