Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family

Set1A and Set1B, two members of the COMPASS family of methyltransferases that methylate the histone H3 lysine 4 (H3K4) residue, have been accredited as primary depositors of global H3K4 trimethylation (H3K4me3) in mammalian cells. Our previous studies in mouse embryonic stem cells (ESCs) demonstrate...

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Vydáno v:Sci Adv
Hlavní autoři: Sze, Christie C., Ozark, Patrick A., Cao, Kaixiang, Ugarenko, Michal, Das, Siddhartha, Wang, Lu, Marshall, Stacy A., Rendleman, Emily J., Ryan, Caila A., Zha, Didi, Douillet, Delphine, Chen, Fei Xavier, Shilatifard, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314515/
https://ncbi.nlm.nih.gov/pubmed/32637595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz4764
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