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High affinity between CREBBP/p300 and NCOA evolved in vertebrates

The interaction between the transcriptional coactivators CREBBP/p300 and NCOA is governed by two intrinsically disordered domains called NCBD and CID, respectively. The CID domain emerged within the NCOA protein in deuterostome animals (including vertebrates) after their split from the protostomes (...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Karlsson, Elin, Lindberg, Amanda, Andersson, Eva, Jemth, Per
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314397/
https://ncbi.nlm.nih.gov/pubmed/32329110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3868
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