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A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins

Many intrinsically disordered proteins (IDPs) attain a well-defined structure in a coupled folding and binding reaction with another protein. Such reactions may involve early to late formation of different native structural regions along the reaction pathway. To obtain insights into the transition s...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Karlsson, Elin, Andersson, Eva, Dogan, Jakob, Gianni, Stefano, Jemth, Per, Camilloni, Carlo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349112/
https://ncbi.nlm.nih.gov/pubmed/30514761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005854
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