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A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins

Many intrinsically disordered proteins (IDPs) attain a well-defined structure in a coupled folding and binding reaction with another protein. Such reactions may involve early to late formation of different native structural regions along the reaction pathway. To obtain insights into the transition s...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Karlsson, Elin, Andersson, Eva, Dogan, Jakob, Gianni, Stefano, Jemth, Per, Camilloni, Carlo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349112/
https://ncbi.nlm.nih.gov/pubmed/30514761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005854
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