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Deciphering the mechanisms of binding induced folding at nearly atomic resolution: The Φ value analysis applied to IDPs

The Φ value analysis is a method to analyze the structure of metastable states in reaction pathways. Such a methodology is based on the quantitative analysis of the effect of point mutations on the kinetics and thermodynamics of the probed reaction. The Φ value analysis is routinely used in protein...

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Detalhes bibliográficos
Publicado no:Intrinsically Disord Proteins
Main Authors: Gianni, Stefano, Dogan, Jakob, Jemth, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314873/
https://ncbi.nlm.nih.gov/pubmed/28232881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/idp.28624
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