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A Frustrated Binding Interface for Intrinsically Disordered Proteins
Intrinsically disordered proteins are very common in the eukaryotic proteome, and many of them are associated with diseases. Disordered proteins usually undergo a coupled binding and folding reaction and often interact with many different binding partners. Using double mutant cycles, we mapped the e...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937629/ https://ncbi.nlm.nih.gov/pubmed/24421312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537068 |
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